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Preclinical and clinical data are available evaluating the effect of GLP-1RAs on neurobiological systems and behaviors characteristic of nicotine use and cessation

Acta Physiol (Oxford, England) 222(2)

Doubling up or taking doses too close together does not "make up" for the missed dose

They should be used for the right medical reasons, with strong clinical support, and with a long-term plan focused on health, not thinness at any cost

Tirzepatide offers cardiovascular protection (38% reduction in heart failure events), liver fat reduction and MASH resolution (44-62% of patients), sleep apnea improvement (up to 63% AHI reduction), blood pressure reduction (up to 5.8 mmHg), cholesterol improvement (24.9% triglyceride reduction), kidney protection (33% fewer major kidney events), joint pain reduction, PCOS symptom improvement, and systemic inflammation reduction