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Wu and Gao, 2018), indicating that the effects of GH and IGF1 on cell proliferation can not only maintain the growth and development of normal organism, but also promote the process of cancer cells

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Metabolomics confirmed this via reduced GSH recycling intermediates (S-lactoylglutathione, cysteine-GSH disulfide) ( A Stat1-Gpx3 hub was identified, where TNF-/IL-1-induced Stat1 activation suppresses Nrf2 (confirmed by reduced hippocampal Nrf2)

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Supplementation with NAC, cysteine, and glycine has been shown to increase GSH levels