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Contains silybin in a phospholipid complex, which has been shown to provide significantly enhanced bioavailability in dogs and cats compared to standardised milk thistle Contains vitamin E in its formulation, preventing the need for additional supplementation Hepatoadvanced may be used as an adjunctive therapy in conditions such as: Chronic hepatitis Hepatic lipidosis Cholangiohepatitis Paracetamol toxicity Hepatotoxic mushroom ingestion Copper related hepatopathy Iron overload - Medication use including NSAIDs, phenobarbital and corticosteroids (note: does not prevent corticosteroid-induced hepatic vacuolar change) Metabolic hepatopathies Other acute or chronic hepatopathies Neoplasia Canine cognitive dysfunction Cirrhosis Hepatoadvanced can be used concomitantly with other common hepatic supportive treatments, such as prescription diets, ursodeoxycholic acid, anti-inflammatories, and other non-vitamin E containing nutritional supplements