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Description

NNMTs role is to transfer a methyl group to nicotinamide (vitamin B3), creating 1-methylnicotinamide a reaction that consumes cellular methyl donors and depletes nicotinamide adenine dinucleotide (NAD) stores

Allergic reactions to cyanocobalamin have been reported and require immediate medical attention

Patients self-injecting vitamin B12 without telling their GP, finds study A large proportion of patients with a vitamin B12 deficiency self-inject medication sourced online, citing difficulty with accessing treatment from GPs