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The results of western blot and immunofluorescence showed that knockdown of VRK2 resulted in the decline of SLC7A11 expression at PM (Fig

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The need for diagnosis, treatment and prevention of AITD is also due to the need to prevent concomitant diseases, including disorders of the cardiovascular system, hypercholesterolemia, atrial fibrillation, encephalopathy, others autoimmune diseases ( Cellular and humoral immunity in the pathogenesis of AITD In addition to genetic, cellular and humoral immune mechanisms, loss of immune tolerance to thyroid autoantigens is the basis for the development of AITD

For comparison, the human genome contains 48 ABC transporter genes including only two members of the MDR family (Rea, 2007)

Wixner J., Suhr O