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Most common side effects were gastrointestinal, with 24.5% of participants in the phase 2 obesity trial discontinuing efinopegdutide 10 mg due to AE however when the same dose was used with gradual escalation at the MASLD trial (starting dose 2.4 mg for 4 weeks, then 5 mg for 4 weeks and then 10 mg), only 5.6% of participants discontinued the medication due to AE

Net lactate accumulation was calculated as the difference between lactate measurements 14 min post exercise and resting values divided by the average MP values of the five sprints

doi: 10.1007/s11695-017-2607-8

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