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One study looked at vildagliptin in rats with a Huntingtons like condition and found improved motor and cognitive performance and less striatal damage through the PI3K/Akt pathway

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In preclinical models of polymicrobial sepsis, such as the cecal slurry and cecal ligation puncture (CLP) models, long-acting GLP-1 receptor agonists (GLP-1RAs) like semaglutide have demonstrated protective effects

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