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Surgery is usually reserved for patients who have very large goitres (enlarged thyroid glands) that cause compression symptoms such as difficulty breathing or swallowing, who have eye problems due to Graves disease (Graves ophthalmopathy), who have suspicious nodules or cancer in the thyroid gland, or who are not suitable for or refuse anti-thyroid drugs or radioactive iodine therapy

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This work was supported by the National Institutes of Health of the USA (R01CA160417 and R01GM115366 to DT), The National Natural Science Foundation of China (31171229 and U1132005 to XS), and a Science and Information Technology of Guangzhou Key Project (201508020258 and 201400000003/4 to XS)

Microneedling with PDRN and Exosomes Microneedling creates micro-channels that break up pigmentation clusters and open the dermis for maximal penetration of brightening serums and PDRN