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Health Risks: Efficacy Loss, Contamination, and Consistency Using expired compounded semaglutide poses three primary risks: reduced therapeutic efficacy (weakened weight-loss or glycemic benefits), increased contamination risk (bacterial growth or chemical byproducts), and dosing inconsistency (unmeasurable potency)

doi: 10.1007/s00394-022-02804-3 [DOI] [PMC free article] [PubMed] [Google Scholar] 299

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Understanding the impact of renal or hepatic impairment on the pharmacokinetic properties of cagrilintide is crucial for managing overweight and obesity in individuals with these conditions, particularly as chronic kidney disease and liver disease including metabolic dysfunction-associated steatotic liver disease are common comorbidities of obesity