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In vitro studies further revealed that schisandrin B suppressed oxidative stress and inflammation in BV2 microglia and PC12 cells [63, 64] and protected against microglial-mediated inflammatory damage in microglianeuron cocultures by downregulating NADPH oxidase and other mediators, such as NO, TNF-, PGE-2, IL-1 and IL-6 [37]

[PubMed ID: 37569510]