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However, in the 25 to 33% of patients who experience shunting with thiopurine monotherapy (preferential metabolism to less effective and potentially toxic thiopurine metabolites), low doses of thiopurines in combination with allopurinol may be prescribed to improve therapeutic effect

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The abdomen offers the largest injection area and is often the easiest site for self-injection

J Am Heart Assoc 10(13):21084 Perkovic V, Tuttle KR, Rossing P et al (2024) Effects of semaglutide on chronic kidney disease in patients with type 2 diabetes

GIP receptor activation appears to amplify GLP-1 weight loss effects and reduce GLP-1-related nausea