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DPP-4 inhibition contributes to the prevention of hypoglycaemia through a GIP-glucagon counterregulatory axis in mice

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With the advent of longacting therapies that include glucagonlike peptide1 (GLP1) receptor agonist activity (e.g., semaglutide and the glucosedependent insulinotropic polypeptide [GIP]/GLP1 receptor dual agonist tirzepatide), greater and more sustained weight loss has become achievable medically

A double-blind, randomized, placebo and positive-controlled study in healthy volunteers to evaluate pharmacokinetic and pharmacodynamic properties of multiple oral doses of Cetagliptin