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For many people, this means the weight comes back too, unless theyve made other changes to maintain it

They may have serious side effects, including possible thyroid tumors

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Skin tightening treatments can help mild laxity, while more pronounced sagging may benefit from procedures like a neck lift to effectively tighten skin after weight loss

Comparative Efficacy and Safety of Different Orforglipron Doses in Patients With Type 2 Diabetes Mellitus and Obesity: A Systematic Review and Network Meta-Analysis