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Adenovirus-mediated expression of CYP2E1 produces liver toxicity in mice

In addition to their established benefits for the management of diabetes and obesity, GLP-1RAs have shown potential in managing MASLD through mechanisms such as reducing hepatic lipogenesis, improving insulin sensitivity, and modulating inflammation

Wang, Z., Al-Regaiey, K

The SASP consists of a plethora of secreted factors, including pro-inflammatory cytokines, chemokines, growth factors, and extracellular matrix-degrading proteases, which profoundly influence the tissue microenvironment [56]