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Almost all efficacy data come from a single research group, and independent replication of the larger-effect-size studies remains limited

When the liver is overburdened (due to poor diet, environmental toxins, alcohol consumption, or metabolic stress), fat metabolism can slow down

Lipid Profile & Metabolic Health Some research reports improved lipid balance (e.g., triglyceride reduction) in preclinical studies. Possible improvements in basal metabolic rate have also been noted