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Labs should include standard lupus markers (complement, anti-dsDNA, CBC, urinalysis) plus metabolic markers (glucose, HbA1c, lipid panel, liver enzymes)

Magnesium levels drop alongside sodium during GLP-1-induced natriuresis, and low magnesium exacerbates cerebral vasoconstriction and neuromuscular tension that worsen headache intensity

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Astragaloside IV can also reversed bleomycin-induced weight loss in rats and reduced the lung wet-to-dry weight ratio, indicating alleviation of pulmonary edema