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Whether this is a direct action of metformin on GLP-1 release, and whether some of the glucose-lowering effect of metformin occurs due to GLP-1 release, is unknown

1519 Using myocardial contrast echocardiography (MCE), a noninvasive technology that employs perfluorocarbon gas containing microbubbles to noninvasively assess in vivo perfusion of the cardiac microvasculature, 20,21 we showed that insulin potently increases cardiac microvascular perfusion in healthy humans

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Tailoring adjuvant endocrine therapy for premenopausal breast cancer