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For the BH False Discovery Rate correction, the total number of variables (m) was set to 11, corresponding to all metabolites and macromolecular signals included in the univariate analyses (those with CRLB 20%, except for Cr and GSH in the Hip of WKY/CMS rats, CRLB 22%, and Gln in the Hip of WKY/CMS rats, CRLB 25%)

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While previous studies have shown benefits of liraglutide in this group, BARI-STEP is the first randomised controlled trial of semaglutide in patients following bariatric surgery

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