He identified the active compound as GHK-Cu and spent the next five decades documenting its effects on skin, wound healing, and gene expression
In elective TJA, where tolerance for biologic uncertainty is low, the most defensible approach remains risk minimization
GHK-Cu (Glycyl-L-Histidyl-L-Lysine Copper) GHK-Cu is a naturally occurring copper complex first identified in human plasma
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(1) More specifically, the tripeptide sequence composed of glycine, histidine, and lysine, abbreviated as Gly-His-Lys, may be derived during the breakdown of collagen through hydrolysis