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Eur J Pharmacol 991: 177305

C.EssenwangerJ.StolzJ.et al (2017)

By carrying antioxidants, immunomodulatory drugs, or targeting moieties, these NPs shift microglia away from neurotoxic phenotypes and bolster clearance of pathogenic proteins

Its mechanism of action is mainly through the regulation of glycolysis-related enzymes - adenylate-activated protein kinase (AMPK), which in turn promotes the process of glycolysis, enabling the energy supply of cardiomyocytes to increase, thereby exerting the anti-ischemic protective effect on the heart (123)