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With a Fiscal Year 2017 Lupus Research Program Concept Award, Dr

doi: 10.1001/jama.2019.14725 12 WildingJPHBatterhamRLCalannaSDaviesMVan GaalLFLingvayIet al

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In terms of iron metabolism and homeostasis in immune cells, a study revealed that iron overload promotes abnormal differentiation of pathogenic T cells, including follicular helper T cells, by regulating DNA demethylation, thus exacerbating autoantibody production and the development of systemic lupus erythematosus (SLE) [26]