In the present work, we use zebrafish as our model organism, which have a similar homology to humans [54,55]
A randomized, double-blind, placebo-controlled study of histone deacetylase type 6 inhibition for the treatment of painful diabetic peripheral neuropathy
Furthermore, the complement system is actively involved in DN pathogenesis by modifying DNA methylation patterns in renal tubular cells
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a meta-analysis demonstrated its significant role in reducing exacerbations [14]