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A number of complex physiological mechanisms have been suggested to promote weight regain after weight loss, including hormonal changes, changes in resting energy expenditure, and neuronal factors affecting hunger and reward

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Supplementation is often recommended for people with deficiencies, athletes, or those on restrictive diets like vegan or ketogenic diets

Manufacturer patient assistance programs and copay savings cards can reduce costs for eligible patients, though these programs have specific eligibility criteria and may not be available for government insurance beneficiaries due to federal anti-kickback regulations

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