Pyrrolinone-Pyrrolidine Oligomers as Universal Peptidomimetics
Clinical manifestations range from asymptomatic elevations in serum transaminases to more severe conditions, including cholestatic jaundice, peliosis hepatis, hepatic adenomas, and, in rare cases, hepatocellular carcinoma (75)
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These chromosomal structures are known to be crucially involved in the process of cellular senescence (Victorelli and Passos, 2017) and their age-associated shortening is commonly regarded as an important contributor to organismal aging (McHugh and Gil, 2018)
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