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Most of the time, these effects are mild
In addition, since iron is heterogeneously distributed across brain regions and cell types (Levi et al., 2024), potential off-target chelation could result in iron depletion in brain regions where iron supports physiological function and consequently affect neuronal and glial metabolism, neurotransmitter synthesis, or cell signaling
FDA treats any injectable product as a drug
In aging rodents, butyrate administration improved learning and memory, presumably by upregulating brain-derived neurotrophic factor (BDNF) and other plasticity-related proteins [76, 107]