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Song G, Yang D, Wang Y, de Graaf C, Zhou Q, Jiang S, et al
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Additionally, hypertrophic adipocytes release TNF-, IL-6, and MCP-1, reinforcing the inflammatory state and perpetuating insulin resistance Figure 3 ( Figure 3 Recent single-cell transcriptomic studies have identified distinct macrophage populations such CD9 + macrophages in obese adipose tissue that display both inflammatory and pro-fibrotic phenotypes (36, 37)
