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The melanocytic nests are discohesive, often irregular in size and shape, sometimes adopt a crescentic shape, and may coalesce (Fig

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Ocrevus (ocrelizumab) Disease area(s): Neurology/immunology Manufacturer(s): Roche 2024 Sales (USD): $7.66 billion Why it sold so well: In 2024, Roches multiple sclerosis (MS) therapy Ocrevus achieved sales of CHF 6.74 billion ($7.66 billion), marking a 9% increase from the previous year