Multiple large epidemiological studies now link circulating MMA to all-cause mortality, independent of serum B12
Many clinicians recommend continuing as long as its safe, effective, and needed, just like any other chronic condition treatment

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Interestingly, while ROSE-010 effects seem to be dose dependent in previous studies, we did not find a correlation between the amount of change in GLP-1 and amount of IBS-SSS reduction (9, 10)
Complex multi-party cases involving extensive discovery can take 18-36 months