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When this control is changed by oxidative or electrophilic signals, Nrf2 can accumulate and increase the expression of antioxidant-response genes, including those involved in GSH synthesis

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As concerns fibrosis evaluation through cross-sectional imaging techniques, especially magnetic resonance elastography, their use is limited at the moment to tertiary referral centers and for experimental studies, in light of their cost, the limited availability and the procedural length

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