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Uchiyama et al

However, this scenario was only tested as a sensitivity analysis due to the uncertainty around changes in physiological parameters on initiation of insulin, as there is a paucity of evidence around the impact of adding a basal insulin to continued GLP-1 receptor agonist therapy

In the US, similar dynamics are playing out: the EPA added DMAC, a close structural analog of DMF, to its hazardous substances list in 2024

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