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Alprostadil can be administered by intracavernosal injection (self-injected into the penis) or intraurethral application (a small pellet inserted into the urethra)

One of its key advantages is its selectivity, meaning it stimulates growth hormone release without significantly increasing cortisol or prolactin levels

Wegovy and Zepbound are well-established options in this field

6 According to this new framework, people with a BMI of 25 or higher would be classified as having obesity if they also: Have a waist-to-height ratio of 0.5 or greater Have been diagnosed with medical, functional, or psychological issues related to excess body fat, such as elevated blood glucose, chronic low-grade inflammation, poor sleep, or binge eating

15,73 Adherence is much lower in practice: about 33-50% at 1 year and 15% at 2 years