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The Wnt/-Catenin signaling pathway plays crucial roles in HFs development, including growth cycle restart and maintenance and HF cells proliferation and differentiation (Zhu et al., 2016), and myricitrin (Zhang et al., 2016) could regulate Akt

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The histidine residue serves as the primary copper-binding site through its imidazole ring, creating a stable square-planar copper(II) complex with the amino terminal and adjacent peptide nitrogen atoms

In their free form, some amino acids also work as signaling molecules and some, such as tryptophan, are important precursors for the synthesis of neuroactives [93, 94]

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