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Gastrointestinal perception: pathophysiological implications

[] In another study, 24 volunteers were recruited18 for dosage escalation to ascertain the maximum tolerated dose (MTD) and six for pharmacokinetic assessment

This reduction was associated with downregulated NFB expression and partial suppression of MAPK and AP-1 signaling, elucidating that GAC1 may have potential for treating TNF- mediated inflammation [110]