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When injected, it binds to GHRH receptors on the pituitary and triggers a pulse of growth hormone release, which in turn drives the production of IGF-1 (insulin-like growth factor 1), the downstream hormone responsible for most of growth hormones tissue effects

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NO / eNOS axis modulation BPC-157 normalizes nitric oxide production, a vascular and mucosal protective effect demonstrated in ischemia-reperfusion and gastroduodenal injury models

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Real-time PCR arrays reveal upregulation of MMP-2 and MMP-9 transcripts, while zymography assays confirm corresponding increases in enzymatic activity levels within conditioned media samples