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It increases the Bcl-2/Bax ratio and decreases Bax and cleaved-caspase-3 protein levels, which in turn promotes skeletal muscle autophagy and mitophagy, inhibits apoptosis, and improves the functional status of skeletal muscle mitochondria and skeletal muscle atrophy (Marshall et al., 2022)

2007;69(3):S619

Remind older adults to think positively and relax with fun activities like puzzles and other games

Specific studies on exenatide have also reported superior menstrual regularity compared to metformin after 1224 weeks of treatment (128, 129)

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