It slows gastric emptying, meaning food sits in the stomach longer and satiety signals reach the brain sooner
GLP-1RAs in nervous system In the nervous system, GLP-1 can decrease oxidative stress and inflammatory responses, potentially through reducing the generation of ROS and decreasing the expression of inflammatory cytokines
A recent trial on the treatment effect of semaglutide in people with obesity reported the significant effects of the long-acting GLP-1RA semaglutide on body weight and related phenotypes (169)
High-quality protein sources include: Lean poultry (chicken, turkey) Fish and seafood (salmon, cod, shrimp) Eggs and egg whites Greek yogurt and cottage cheese Legumes (lentils, chickpeas, black beans) Lean cuts of beef and pork Note: Individuals with chronic kidney disease should consult their healthcare provider before significantly increasing protein intake
If cost or access issues force a stop, even a partial taper over two to three weeks is better than nothing