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90 Lipoic acid stabilized neuronal plasma membranes, prevented NADPH oxidative stress, and improved behavior following mild TBI in rats

References Journal of Pharmacological Sciences Klicek R et al

While optimizing those nutrient inputs and exercise can help support healthy NAD+ levels, for most adults, this probably wont be enough

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And when broken down by lean mass vs fat mass loss by DEXA scan it was similar to semaglutide 70% fat, 30% lean, which is also in line with bariatric surgery