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Supplementary Figure S4)

Supply conditions and regulatory status for compounded GLP-1s can shift, so any compounding arrangement should be treated as subject to change and verified at the source

Peptide purity and source quality Perhaps no factor matters more than what is actually in the vial

Past medical history should address previous gastrointestinal conditions, bleeding episodes, liver disease, and colorectal cancer screening status

For example, if you are someone who usually eats one or two large meals in the day, and those meals tend to be higher in fat, it may be time to adopt a new eating pattern centered on small, frequent, nutrient-dense meals