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5 (The lead authorship of this meta-analysis has industry ties to a myo-inositol manufacturer, and the German cohort cited below was led by an investigator at a myo-inositol distributor

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Beyond metabolic regulation, SCFAs exert anti-inflammatory effects by interacting with G-protein-coupled receptors (GPCRs) and inhibiting histone deacetylases (HDACs), which regulate immune and inflammatory pathways (Yao et al., 2024

Unlike EOAD, LOAD is sporadic in nature and results from a multifactorial etiology involving age, vascular health, metabolic syndrome, and gene-environment interactions (Marshe et al., 2019

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