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Induction of shear stress by exposure to fluid movement decreased apoptosis, enhanced proliferation, and the mobility of endothelial cells in these models but did not alter the expression of TJ proteins or P-gp (DeStefano et al., in vivo levels after ~12 days, and integrity is maintained over 3 weeks in culture

The most common side effects are mild digestive symptoms such as nausea, constipation, diarrhea, or stomach upset, especially when starting or increasing the dose

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17, 571577 10.1097/MOH.0b013e32833ec217 [DOI] [PubMed] [Google Scholar] Towbin H., Staehelin T., Gordon J