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This focused subset yielded a highly significant enrichment of metabolic and mitochondrial programs, including metabolism, aerobic respiration and respiratory electron transport and additional pathways related to mitochondrial protein turnover and Complex IV assembly (Supplementary Figure S5)

Expression of SOD and catalase is indirectly regulated by SIRT3 through deacetylation of FOXO3 106,107

GiustariniDTsikasDColomboGMilzaniADalle-DonneIFantiPet alPitfalls in the analysis of the physiological antioxidant glutathione (GSH) and its disulfide (GSSG) in biological samples: an elephant in the room

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