Targeted carnitine tandem mass spectrometry analysis in the patient revealed complete absence of plasma-free carnitine and only trace levels of total carnitine, further supporting the causality of the SLC22A5 variant
Nat Med (2026).
Newsome P, Francque S, Harrison S, Ratziu V, Van Gaal L, Calanna S, Hansen M, Linder M, Sanyal A (2019) Effect of semaglutide on liver enzymes and markers of inflammation in subjects with type 2 diabetes and/or obesity
However, whether ferroptotic cell death is triggered by A aggregation, or tau hyperphosphorylation or whether there is an interaction between them remains yet to be confirmed
Together with B-vitamin fortified food (e.g., cereal, nutritional yeast) and supplements, these foods might contribute, though modestly, to prevent vitamin B 12 deficiency in individuals consuming vegetarian diets