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If NOX expression is not properly regulated, NOX-associated ROS can promote OS, aberrant signaling, and genomic instability [229]

10.1016/j.bios.2013.03.057 67 LiX.WenF.CreranB.JeongY.ZhangX.RotelloV

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Cell-mediated immunity primarily needs protein antigen degradation in the endocytic vesicles of antigen presenting cells (macrophages, dendritic cells), to be able to present smaller peptides on the cell surface through major histocompatibility complex antigens to activate antigen-specific T cell proliferation