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The group that was administered Mirtoselect exhibited considerable enhancements in Schirmer test scores, signifying improved tear production relative to the placebo group

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Hydroxyzine (Evidence Strength: Grade C) One randomized controlled trial reported that more patients in the treatment group (23%) experienced clinically significant improvement compared to patients in the placebo group (13%) in response to oral hydroxyzine for six months (10 mg daily titrated to 50 mg daily over several weeks if tolerated)

Abdullahi M, et al

Whilst gastrointestinal side effects such as nausea and diarrhoea are well-recognised, some patients report joint pain during treatment