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Statistical Methods Change from baseline in SGRQ Total score and each component score were analyzed using analysis of covariance, with change from baseline as the response variable and with factors for treatment group, high-risk CV comorbidities (yes/no), background LABA use (yes/no), and baseline score as covariates

There may also be a mismatch between the drug mechanism and the disease driver

doi:10.3746/pnf.2021.26.2.109

The degree of weight loss depends on your genetics, the steroid dose and duration, your baseline metabolism, and how well you respond to GLP-1 therapy

Analyses of these data showed consistent associations across all categories studied