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The study included substantial preclinical work and a small proof-of-concept human component, so it should not be generalized to every older, frail, or medically complex patient

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However, medications used for the domiciliary management of early symptoms, notwithstanding their importance, have not been and are not presently regarded with the same attention and seriousness

333,334,335,336 Specifically, glial cells engage in cross-talk with synapses through surface-expressed ion channels, receptors and transporters