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13 Cryotherapy delivered in freeze-thaw cycles (Table 2) is effective at destroying malignant cells in superficial BCC because cellular damage occurs both during the freezing process and during the slower thaw, due to the osmotic gradient across the cell membrane

It also requires caution in patients with prior pancreatitis, severe gastroparesis, advanced diabetic retinopathy, or those on insulin and other glucose-lowering medications

Driver sleepiness is a factor in about 100,000 car accidents each year, resulting in about 1,500 deaths

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Initial studies showed that ECs should be taken within 72 hours after intercourse