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17 Obesity Obesity is a major contributing factor for CKD, explained in part by the observation that obesity predisposes individuals to diabetes and hypertension

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Thioredoxin Reductases (TXNRD1, TXNRD2, and TXNRD3) TXNRD1 and TXNRD2 are available in the cytosol and the mitochondria of mammalian cells, are essential for cellular redox balance, and are both highly expressed in the heart

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