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- The assay is run as described in the General ELISA Protocol

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Notably, however, we found that the co-therapy of acyl-GLP-1 (10 nmol kg 1 ) and the acylated GIPR antagonist (1,500 nmol kg 1 ) equally decreased body weight in DIO WT and Per-Gipr KO mice, with superiority of the co-therapy relative to treatment with acyl-GLP-1 alone (Fig