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There are great variations in nuclear GSH concentration and its regulation mechanisms during the cell cycle since cells starting the proliferation phase have high levels of nuclear GSH, while resting cells have similar or lower GSH levels in the nucleus than in the cytoplasm (68, 72, 73)

Current clinical guidance recommends restarting at the lowest dose when switching medications

If you're pregnant, nursing, taking medication, or have a medical condition, it's better to consult a healthcare professional